Tom Fleck,Bruce Fleck,Magnus Cernerud,Helena Lundström,Claes Löfström,Margit Pelcman,Alexander Paptchikhine,Emma Andersson,Alf Nygren
申请号：
US13234510
公开号：
US20120004241A1
申请日:
2011.09.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system.In one aspect, the invention relates to a process for the preparation of compounds of the general formula (I):wherein HA is a pharmaceutically acceptable acid and R1-R4 are each independently selected from the group consisting of hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, and di-C1-C6-alkylamino-C2-C6-alkoxy.The invention also relates to the use of said compound to manufacture a medicament for the treatment of a serotonin-related disorder.
