KORMAN, ALAN J.,SELBY, MARK J.,LU, LI-SHENG,WITTE, ALISON,HUANG, HAICHUN
申请号:
CA2630483
公开号:
CA2630483C
申请日:
2006.12.08
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present disclosure provides isolated monoclonal antibodies, particularlyhuman monoclonal antibodies that specifically bind to O8E with high affinity.Nucleic acid molecules encoding the antibodies of this disclosure, expressionvectors, host cells and methods for expressing the antibodies of thisdisclosure are also provided. Immunoconjugates, bispecific molecules andpharmaceutical compositions comprising the antibodies of this disclosure arealso provided. This disclosure also provides methods for treating cancer.