Alan J. Korman,Mark J. Selby,Li-Sheng Lu,Alison J. Witte,Haichun Huang
申请号:
US15048785
公开号:
US20160168249A1
申请日:
2016.02.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically bind to O8E with high affinity. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided. This disclosure also provides methods for treating cancer.