THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
SCHAFFER, DAVID V.,FLANNERY, JOHN G.,BELTRAN, WILLIAM A.,BYRNE, LEAH C.,VISEL, MEIKE
申请号：
CA3029833
公开号：
CA3029833A1
申请日:
2017.07.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.
