SCHAFFER DAVID V,KLIMCZAK RYAN R,KOERBER JAMES T,FKANNERY JIOHN G,DALKARA MOUROT DENIZ,VISEL MEIKE,BYRNE LEAH C T
申请号：
ZA201307968
公开号：
ZA201307968B
申请日:
2013.10.24
申请国别(地区):
ZA
年份:
2015
代理人:
摘要：
The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via intravitreal injection, compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease.
