The invention discloses beverage or oral liquid with the effects of reducing fat and protecting the liver and a preparation method of the beverage or oral liquid. The preparation method comprises the steps of crushing to be micrometer level, carrying out biological enzymolysis, adsorbing and clearing, carrying out high-speed centrifugation and ultrafiltration and the like. The preparation method of the beverage or oral liquid disclosed by the invention has the advantages that the integrated application of the five type technologies is adopted, and seen from the two indexes such as extract yield and total flavone yield, the new method is better than the conventional method, the original components of the medicines can be furthest retained by combined use of two types of flocculating agents, the capability of absorbing impurity components such as tannin influencing the taste is enhanced, so that the prepared beverage or oral liquid disclosed by the invention has the advantages that the taste is greatly improved, the astringent flavor is greatly reduced, and the unexpected effects of extraction, taste and clarification of the effective components are achieved.