DERIVATIVE OF INDOL THAT HAS ANTAGONIST ACTIVITY OF THE PGD2 RECEIVER.

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专利权人:

LTD.;SHIONOGI & CO.

发明人:

KUGIMIYA, AKIRA,SHICHIJO, MICHITAKA,HIRAMATSU, YOSHIHARU,ISHIZUKA, NATSUKI

申请号：

ES06781305

公开号：

ES2372701T3

申请日:

2006.07.20

申请国别(地区):

ES

年份:

2012

代理人:

摘要：

A compound of generic formula (I): in which ring A is a benzene ring； Ring B is a ring of formula: R1, R2, R3, R4 and R5 are independently a hydrogen atom, a halogen atom, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, hydroxy, optionally substituted alkyloxy, optionally substituted alkenyloxy, optionally substituted alkynyloxy, optionally substituted cycloalkyloxy, optionally substituted cycloalkenyloxy, mercapto, optionally substituted alkylthio, optionally substituted alkenylthio, optionally substituted alkynylthio, optionally substituted alkylsulfinyl, optionally substituted alkylsulphonyloyl substituted, optionally substituted cycloalkylsulfinyl, optionally substituted cycloalkylsulfonyl, optionally substituted cycloalkylsulfonyloxy, optionally substituted cycloalkenylthio, ci optionally substituted chloalkenylsulfinyl, optionally substituted cycloalkenylsulfonyl, optionally substituted cycloalkenylsulfonyloxy, optionally substituted amino, acyl, optionally substituted alkyloxycarbonyl, optionally substituted alkenyloxycarbonyl, optionally substituted alkynyloxycarbonyl, optionally substituted, optionally substituted aryloxy optionally substituted arylthio, optionally substituted arylsulfinyl, optionally substituted arylsulfonyl, optionally substituted arylsulfonyloxy, optionally substituted heteroaryl, optionally substituted heteroaryloxy, optionally substituted heteroarylthio, optionally substituted heteroarylsulfinyl, optionally substituted heteroarylsulfonyl or optionally substituted heterocyclic heterocyclic group； R6 is C2-C6 alkyloxy, substituted C1-C6 alkyloxy, optionally substituted C2-C6 alkenyloxy, optionally substituted C2-C6 alkynyloxy, optionally substituted C3-C6 cycloalkyloxy, optionally substituted C3-C6 cycloalkenyloxy, optionally substituted aryloxy, optionally substituted heteroaryloxy C2-C6, substituted C1-C6 alkylthio, opt

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