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COMPOUND, PRODUCT, PHARMACEUTICAL AGENT, METHODS TO INHIBIT AN ANGIOTENSIN II RECEIVER AND / OR ACTIVATE A PEROXISOMAL ACTIVATED RECEIVER, AND TO PREVENT OR TREAT DISEASE OR CONDITION, AND, USE OF A COMPOUND
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
TAKANOBU KUROITA,HIROKI SAKAMOTO,HIDEYUKI IGAWA,MINORU SASAKI,KOUHEI ASANO,TSUYOSHI MAEKAWA
申请号:
BRPI0719060
公开号:
BRPI0719060A2
申请日:
2007.11.21
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
A compound represented by the formula (I): wherein R1 is an oxo group, =N-R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, -CO-R8 or -O-R8', or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of circulatory diseases, metabolic diseases and/or central nervous system diseases.
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