Ramanuj Dasgupta,Foster Gonsalves,Susan Katherine Logan,Eugine Lee
申请号：
US13448737
公开号：
US09173871B2
申请日:
2012.04.17
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A series of oxazole and thiazole compounds are shown herein to be small molecule inhibitors of the Wnt pathway that specifically target the activity of the stabilized pool of β-catenin. Oxazole and thiazole compounds are disclosed that have a formula represented by the following:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, cancer, and others.
