Gregory L. Verdine,Tom N. Grossmann,Tsung-Han Johannes Yeh
申请号:
US13825709
公开号:
US08957026B2
申请日:
2011.09.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to β-catenin targeting peptides comprising an α-helical segment that are optionally stapled or stitched, and pharmaceutical compositions thereof. Uses of the inventive β-catenin targeting polypeptides including methods for treatment of disease, such as diseases associated with aberrant Wnt signaling, including cancer, are also provided.