Helena Van Den Bussche,Christian Palsson,Johan Borgstrom,Birgitta Svensson,Anna Holmberg,Ake Lindahl,Bernt Thelin
申请号：
US13803328
公开号：
US20130202650A1
申请日:
2013.03.14
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to a composition for improved transdermal drug delivery comprising a drug, a combination of at least two penetration enhancing agents, wherein at least on the of the penetration enhancing agents is selected from the group consisting of esters of saturated or unsaturated fatty acids and lower alcohols, and iso-form alcohols wherein at least one of the penetration enhancing agents is selected from the group consisting of aliphatic diols and triols and wherein the components are present in a non-aqueous solvent system. A preferred topical composition comprises the active substance imiquimod and the penetration enhancing agents isoproply myristate and propylene glycol.
