PARK, YOUNG JUN,JEONG, JIN-KYO,CHOI, YOUNG MI,LEE, MINSEOB,KIM, YEON JUNG,KIM, KYOUNG SUK,CHOI, JOON HUN,LEE, JIN SEO,CHO, EUN JOO,SONG, HYUNNAM,PARK, SUNG JUN,LEE, JONG-HYOUP,LEE, MATTHEW SANGYUP,LEE
申请号:
EP14735132
公开号:
EP2927227A4
申请日:
2014.01.02
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to an antibody-linker-drug conjugate in which an antibody and a cytotoxic drug are conjugated through an enzyme cleavable peptide linker capable of directly binding to a lysine residue of an antibody, a preparation method therefor, and an anticancer drug composition containing the same as an active ingredient.