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ANTIBODY-LINKER-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND ANTICANCER DRUG COMPOSITION CONTAINING SAME
专利权人:
发明人:
Young Jun PARK,Jin-kyo JEONG,Young Mi CHOI,Minseob LEE,Yeon Jung KIM,Kyoung Suk KIM,Joon hun CHOI,Jin Seo LEE,Eun Joo CHO,Hyunnam SONG,Sung Jun PARK,Jong-hyoup LEE,Matthew Sangyup LEE,In-Suk LEE,Joon
申请号:
US14655357
公开号:
US20150366990A1
申请日:
2014.01.02
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to an antibody-linker-drug conjugate in which an antibody and a cytotoxic drug are conjugated through an enzyme cleavable peptide linker capable of directly binding to a lysine residue of an antibody, a preparation method therefor, and an anticancer drug composition containing the same as an active ingredient.
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