The present invention relates to a use of Chinese medicine composition in preparation of medicine for secondary prevention of myocardial infarction. Said Chinese medicine composition is prepared from a formula comprising the crude drugs by the following weight percentages: Radix Astragali 22.2%∼66.8%, Radix Salviae Miltiorrhizae 11.6%∼33.4%, Radix Notoginseng 2.5%∼13.5%, and Lignum Dalbergiae Odoriferae 14.5%∼44.3%.