The present invention relates to a use of Chinese medicine composition in preparation of medicine for secondary prevention of myocardial infarction. Said Chinese medicine composition is prepared from a formula comprising the crude drugs by the following weight percentages: Radix Astragali 22.2%ˆ¼66.8%, Radix Salviae Miltiorrhizae 11.6%ˆ¼33.4%, Radix Notoginseng 2.5%ˆ¼13.5%, and Lignum Dalbergiae Odoriferae 14.5%ˆ¼44.3%.