ANTIBODIES CAPABLE OF BINDING HLA-A2/TYRD IN AN HLA RESTRICTED MANNER AND USES THEREOF

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专利权人:

INC.;ADICET BIO

发明人:

Aya Jakobovits,Orit FOORD,Daulet Kadyl Satpayev,Mira Peled Kamar,Galit Denkberg,Yoram Reiter,Ilan Beer,Keren Sinik,Yael Teboul (Elbaz),Yael Shperber (Sery),Reut Erel Segal,Ravit Oren,Dror Shmuel Alish

申请号：

US16622892

公开号：

US20200207858A1

申请日:

2017.06.14

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Antibodies capable of binding HLA-A2/Tyrosinase (TyrD) in an HLA restricted manner are provided. Specifically, the antibodies are capable of binding HLA-A2/TyrD369-377 in an HLA restricted manner. Further provided are complementary determining region (CDR) sequences of heavy chain and light chain of antibodies, and methods of using the antibodies for the treatment of cancer.

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