Antibodies capable of binding HLA-A2/TyrD in an HLA restricted manner and uses thereof

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专利权人:

ADICET BIO INC.

发明人:

JAKOBOVITS, Aya,FOORD, Orit,SATPAYEV, Daulet Kadyl,PELED KAMAR, Mira,DENKBERG, Galit,REITER, Yoram,BEER, Ilan,SINIK, Keren,TEBOUL (ELBAZ), Yael,SHPERBER (SERY), Yael,EREL SEGAL, Reut,OREN, Ravit,ALISH

申请号：

SG11201912069V

公开号：

SG11201912069VA

申请日:

2017.06.14

申请国别(地区):

SG

年份:

2020

代理人:

摘要：

Antibodies capable of binding HLA-A2/Tyrosinase (TyrD) in an HLA restricted manner are provided. Specifically, the antibodies are capable of binding HLA-A2/TyrD369-377 in an HLA restricted manner. Further provided are complementary determining region (CDR) sequences of heavy chain and light chain of antibodies, and methods of using the antibodies for the treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/