Guy M. Miller;Sidney M. Hecht;Orion D. Jankowski;Kieron E. Wesson;Paul Mollard
发明人:
Guy M. Miller,Sidney M. Hecht,Orion D. Jankowski,Kieron E. Wesson,Paul Mollard
申请号：
US11710042
公开号：
US09278085B2
申请日:
2007.02.22
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), or Kearns-Sayre Syndrome (KSS) are disclosed, as well as compounds useful in the methods of the invention. Methods and compounds useful in treating other disorders are also disclosed. Energy biomarkers useful in assessing the metabolic state of a subject and the efficacy of treatment are also disclosed. Methods of modulating, normalizing, or enhancing energy biomarkers, as well as compounds useful for such methods, are also disclosed.
