Generally, the present invention relates to the treatment of respiratory diseases such as asthma and chronic obstructive pulmonary disease. Specifically, the invention relates to a method of treatment and prevention of asthmatic airway inflammation further. Administration of 5-HT4 receptor antagonist to a patient in need of treatment treatment specifically further comprises administration of aroyl of 4-aminomethyl-piperidine derivatives as defined herein. Including pharmaceutical compositions, another aspect of the present invention is directed to a composition for the treatment or prevention of respiratory disorders.本発明は一般的に、喘息及び慢性閉塞性肺疾患のような呼吸器系の疾患の処置に関する。さらに特定的に、本発明は、喘息性気道炎症の処置及び予防の方法に関する。処置は、処置の必要な患者への5-HT4受容体アンタゴニストの投与;さらに特定的に、本明細書で定義されるアロイル化4-アミノメチルピペリジン誘導体の投与を含む。本発明の他の側面は、製薬学的組成物を含む、呼吸器障害の処置又は予防のための組成物を目的とする。
