The invention relates to compositions of epinephrine formulation in an aqueous solution that enhances the chemical stability of epinephrine and consequently extends the product shelf life. The formulation comprises epinephrine or a salt thereof, a tonicity modifier, and a complexing agent, in an aqueous solution adjusted to a pH of about 2-7. A process for manufacturing and methods of using the formulation for the medicinal products are also provided.本發明涉及腎上腺素製劑在水性溶液中的組合物,提供增強腎上腺素的化學穩定性的方法,從而延長產品的保質期。所述製劑包含腎上腺素或其鹽,張力調節劑,和絡合劑,在調整至pH約2-7的水溶液中。還提供了一種用於製造和使用該製劑的醫藥產品的方法。