Liquid compositions for cleaning, in particular medical instruments and air conditioning surfaces, said composition excluding surfactants and comprising one or more enzymes including a protease and optionally a hydrolase, a solvent system including a water soluble glycol ether solvent, at least one anionic hydrotrope, and wherein the molar ratio of said at least one hydrotrope to said glycol ether in the composition is selected to preserve the activity of said one or more enzymes. The hydrotrpe is advantageously an anionic hydrotrope selected from the group consisting of water soluble anionic hydrotropes of the formula:and having no alkyl side chain greater than six carbons in length, for example a xylene sulfonate or cumene sulfonate salt.供清潔用之特別清潔醫療器材及空氣調節表面用之液體組成物,該組成物排除界面活性劑,包含一種或多種苷包括蛋白苷及任選地水解苷,包括水溶性二醇醚溶劑之一溶劑系統,至少一種陰離子性水溶助劑,以及其中於該組成物中,該至少一種水溶助劑對該二醇醚之莫耳比經選擇來保有該一種或多種苷之活性。水溶助劑較佳為選自於由下式水溶性陰離子性水溶助劑所組成之組群之一陰離子性水溶助劑:以及不含長度大於六個碳原子之烷基支鏈,例如二甲苯磺酸鹽或異丙苯磺酸鹽。