Liquid compositions for cleaning, in particular medical instruments and air conditioning surfaces, said composition excluding surfactants and comprising one or more enzymes including a protease and optionally a hydrolase, a solvent system including a water soluble glycol ether solvent, at least one anionic hydrotrope, and wherein the molar ratio of said at least one hydrotrope to said glycol ether in the composition is selected to preserve the activity of said one or more enzymes. The hydrotrpe is advantageously an anionic hydrotrope selected from the group consisting of water soluble anionic hydrotropes of the formula: and having no alkyl side chain greater than six carbons in length, for example a xylene sulfonate or cumene sulfonate salt.
