PHOSPHORAMIDATE NUCLEOSIDE DERIVATIVES AS ANTICANCER AGENTS

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专利权人:

NUCANA PLC

发明人:

GRIFFITH, Hugh,SERPI, Michaela,SLUSARCZYK, Magdalena

申请号：

SG11201810018T

公开号：

SG11201810018TA

申请日:

2017.05.31

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

One aspect of the invention relates to derivatives of cladribine of Formula (I). The compounds are phosphoramidate derivatives in which the phosphoramidate moiety is situated on the 3′-hydroxyl group of cladribine. The invention also relates to pharmaceutical formulations of the cladribine derivatives, and their use in methods of treatment. The compounds are useful in the treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/