GRIFFITH, Hugh,SERPI, Michaela,SLUSARCZYK, Magdalena,MCGUIGAN, Christopher
申请号:
PH12018502606
公开号:
PH12018502606A1
申请日:
2018.11.26
申请国别(地区):
PH
年份:
2019
代理人:
摘要:
This invention relates to derivatives of cladribine of Formula (I). The compounds are phosphoramidate derivatives in which the phosphoramidate moiety is situated on the 3'-hydroxyl group of cladribine. The invention also relates to pharmaceutical formulations of the cladribine derivatives and their use in methods of treatment. The compounds are useful in the treatment of cancer.