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2-heteroarylamino-pyrimidine derivatives as kinase inhibitors
专利权人:
IRM LLC
发明人:
Li, Xiaolin,Loren, Jon,Molteni, Valentina,Nabakka, Juliet,Chianelli, Donatella,Liu, Xiaodong
申请号:
AU2008289135
公开号:
AU2008289135B2
申请日:
2008.08.18
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides compounds of Formula (I) and pharmaceutical compositionsthereof, which are useful as protein kinase inhibitors, as well as methods forusing such compounds to treat, ameliorate or prevent a condition associatedwith abnormal or deregulated kinase activity. In some embodiments, the inventionprovides methods for using such compounds to treat, ameliorate or prevent diseasesor disorders that involve abnormal activation of c-kit, PDGFRα, PDGFRβ,CSF1R, Abl, BCR-Abl, CSK, JNK1, JNK2, p38, p70S6K, TGFβ, SRC, EGFR, trkB,FGFR3, Fes, Lck, Syk, RAF, MKK4, MKK6, SAPK2β, BRK, Fms, KDR, c-raf or b-rafkinases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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