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2-heteroarylamino-pyrimidine derivatives as kinase inhibitors
专利权人:
Donatella Chianelli
发明人:
Donatella Chianelli,Valentina Molteni,Xiaolin Li,Xiaodong Liu,Juliet Nabakka,Jon Loren
申请号:
US12673948
公开号:
US08288540B2
申请日:
2008.08.18
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides compounds of Formula (I) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit, PDGFRα, PDGFRβ, CSF1R, Abl, BCR-Abl, CSK, JNK1, JNK2, p38, p70S6K, TGFβ, SRC, EGFR, trkB, FGFR3, Fes, Lck, Syk, RAF, MKK4, MKK6, SAPK2β, BRK, Fms, KDR, c-raf or b-raf kinases.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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