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NOVEL COMPOUND AS KCNQ POTASSIUM CHANNEL AGONIST, PREPARATION METHOD THEREFOR AND USE THEREOF
专利权人:
CHINESE ACADEMY OF SCIENCES;SHANGHAI INSTITUTE OF MATERIA MEDICA
发明人:
NAN, FAJUN,LI, MIN,GAO, ZHAOBING,CHEN, FEI,ZHANG, YANGMING,ZHOU, PINGZHENG,HU, HAINING,XU, HAIYAN,LIU, SHENG
申请号:
SG11201401759Q
公开号:
SG11201401759QA
申请日:
2012.10.23
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
The present invention provides compounds having the structure represented by general formula I, pharmaceutically acceptable salts thereofagonist, preparation methods therefor and a use thereof in the preparation of a medcine for the treatment of nervous system diseases. The compounds or pharmaceutical compositions thereof can be used as the KCNQ potassium channel agonist for treating nervous system diseases. Compared to retigabine, a compound in the prior art, the compound of the present invention have the same or better therapeutic effect, are easier for synthesis and storage, and less prone to oxidate deterioration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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