Novel compound that can be used as a KCNQ potassium channel agonist, its production method and use

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专利权人:

インスティテュート;マテリア;上海;アカデミー;メディカ、チャイニーズ;オブ;サイエンシーズ

发明人:

ナン，ファージュン,リー，ミン,ガオ，ツァオビン,チェン，フェイ,チャン，ヤンミン,ツォウ，ピンツェン,フウ，ハイニン,スウ，ハイヤン,リウ，シェン,ナン,ファージュン,リー,ミン,ガオ,ツァオビン,チェン,フェイ,チャン,ヤンミン,ツォウ,ピンツェン,フウ,ハイニン,スウ,ハイヤン,リウ,シェン

申请号：

JP2014537451

公开号：

JP5947907B2

申请日:

2012.10.23

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The present invention provides compounds having the structure represented by general formula I, pharmaceutically acceptable salts thereofagonist, preparation methods therefor and a use thereof in the preparation of a medcine for the treatment of nervous system diseases. The compounds or pharmaceutical compositions thereof can be used as the KCNQ potassium channel agonist for treating nervous system diseases. Compared to retigabine, a compound in the prior art, the compound of the present invention have the same or better therapeutic effect, are easier for synthesis and storage, and less prone to oxidate deterioration.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/