Crystalline forms I and II (R) - 1 - ethyl - 3 - 5 - fluoro - [6 - [2 - (1 - hydroxy - 3 - methyl - ethyl) pyrimidin-5-yl] - 7 (tetrahydrofuran-2-ylmethyl 2 - yl) - 1h-benzimidazol-2-yl] urea inhibitor Composition of gyrase； LIFE； and use for treating or reducing bacterial infection.

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专利权人:

VERTEX PHARMACEUTICALS INCORPORATED.

发明人:

SHANNON DEAN,LUISI BRAIN,KRAWIEC MARIUSZ,KULDIPKUMAR ANUJ K

申请号：

CL2013002027

公开号：

CL2013002027A1

申请日:

2013.07.12

申请国别(地区):

CL

年份:

2013

代理人:

摘要：

The present application is directed to solid forms of compounds of formula I: and pharmaceutically acceptable salts thereof, that inhibit bacterial gyrase and/or Topo IV and pharmaceutical compositions comprising said compounds and salts. These compounds and salts are useful in treating bacterial infections.FORMAS CRISTALINAS I Y II DE (R)-1-ETIL-3-[6-FLUORO-5-[2-(1-HIDROXI-1-METIL-ETIL)PIRIMIDIN-5-IL]-7(TETRAHIDROFURAN-2-IL)-1H-BENZIMIDAZOL-2-IL]UREA, INHIBIDOR DE GIRASA； COMPOSICION FARMECEUTICA； Y USO POARA TRATAR O REDUCIR UNA INFECCION BACTERIANA.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/