BRIAN LUISI,DEAN SHANNON,MARIUSZ KRAWIEC,YUSHENG LIAO
申请号：
BR112013017977
公开号：
BR112013017977A2
申请日:
2012.01.13
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
solid forms of gyrase inhibitor (r) 1-ethyl-3- [5- [2- {1-hydroxy-1-methyl-ethyl} pyrimidin-5-yl] -7- (tetrahydrofuran-2-yl) -1h-benzimidazol-2-yl] urea The present application relates to solid forms of compounds of formula (I) and pharmaceutically acceptable salts thereof which inhibit bacterial and / or topo iv gyrase and pharmaceutical compositions comprising said compounds and salts . These compounds and salts are useful in treating bacterial infection.formas sólidas de inibidor de girase (r) 1-etil-3-[5-[2-{1-hidroxi-1-metil-etil}pirimidin-5-il]-7-(tetrai-drofuran-2-il)-1h-benzimidazol-2-il]ureia o presente pedido refere-se a formas sólidas de compostos de fórmula (i) e sais farmaceuticamente aceitáveis dos mesmos que inibem girase bacteriana e/ou topo iv e composições farmacêuticas compreendendo os ditos compostos e sais. esses compostos e sais são úteis no tratamento de infecção bacteriana.
