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FUNCTIONAL POLYMER FILM-COATED PARTICLE HAVING HIGH DRUG CONTENT, TABLET CONTAINING SAME, AND METHODS FOR PRODUCTION THEREOF
专利权人:
发明人:
Tomohiro HAYASHIDA,Junji YAMAZAKI,Yoshio NAKANO,Masaya HIZAKI,Naotoshi KINOSHITA
申请号:
US14889657
公开号:
US20160120813A1
申请日:
2013.05.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided are functional drug-containing particles which can be compressed into tablets and in particular, to orally disintegrating tablets by employing any of a dry molding method, a wet molding method, or a humidifying drying method. The functional drug-containing particles comprise substantially spherical drug-containing particles essentially including drug and a binder, the functional drug-containing particles including a functional polymer film selected from the group consisting of an enteric film, a release control film, and a bitter taste masking film, an average particle diameter of said functional drug-containing particles being 400 μm or less, a particle diameter ratio D90/D10 of the functional drug-containing particles with respect to particle size distribution calculated on a volumetric basis being 1.65 or more, or a coefficient of variation in particle diameters being 24% or more.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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