Thermoembolization systems and techniques may provide simultaneous embolization and ablation of bodily tissue. In some embodiments, thermoembolization may be induced, for example, by arterially infusing a viscous liquid carrying an electrophilic material into the feeding vessel(s) of a tumor. The viscous liquid serves to occlude the arterial supply to the tumor while the electrophilic material concurrently undergoes an exothermic reaction when it comes into contact with water present in bodily tissues. In result, thermoembolization induces simultaneous hypoxic and thermal stresses to the tumor, thereby overwhelming tumor cells.