STELICINSTITUTE & CO.;STELIC INSTITUTE OF REGENERATIVE MEDICINE
发明人:
YONEYAMA, HIROYUKI,FUJII, MASATO
申请号:
EP09847838
公开号:
EP2460403A4
申请日:
2009.07.31
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Fatty liver was induced by administering agents for inducing organ inflammation to experimental animals to evoke insulin resistance and by rearing them with high-fat diets. As a result, steatohepatitis was successfully induced in the animals. The animals show pathological findings similar to those of humans. By using these model animals, substances for treating or preventing diseases can be efficiently screened and the efficacy of medicinal substances can be effectively evaluated.