Ping CHEN,Hengmiao CHENG,Judith Gail DEAL,Gary Michael GALLEGO,Mehran JALAIE,John Charles KATH,Suvi Tuula Marjukka ORR,Hong SHEN,Luke Raymond ZEHNDER
申请号：
US14677112
公开号：
US20150291604A1
申请日:
2015.04.02
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to compounds of formula (X)or pharmaceutically acceptable salts thereof, wherein R1-R50, a, b, d, e, f, g, h, i, j, k, l, o, p, q, r, s, t, u, y, and z are defined herein. The novel dihydropyrrolopyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
