Ping Chen,Hengmiao Cheng,Gary Michael Gallego,Mehran Jalaie,John Charles Kath,Suvi Tuula Marjukka Orr,Mason Alan Pairish
申请号：
US15209574
公开号：
US09758538B2
申请日:
2016.07.13
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to compounds of formula (I)or pharmaceutically acceptable salts thereof, wherein X, Y, Z, R1-R11, m, n, and p are defined herein. The novel pyrimidine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
