Systems and methods are disclosed that determine a mapping between a first camera systems coordinate system and a second camera systems coordinate system or determine a transformation between a robots coordinate system and a camera systems coordinate system, and/or locate, in a robots coordinate system, a tool extending from an arm of the robot based on the tool location in the cameras coordinate system. The disclosed systems and methods may use transformations derived from coordinates of features found in one or more images. The transformations may be used to interrelate various coordinate systems, facilitating calibration of camera systems, including in robotic systems, such as an image-guided robotic systems for hair harvesting and/or implantation.
