use of p27 degradation inhibitors, in particular argirine and derivatives thereof, for the treatment of proliferative diseases.

• 收藏
• 分享

专利权人:

Helmholtz-Zentrum Für Infektionsforschung Gmbh;Medizinische Hochschule Hannover

发明人:

Bettina Hinkelmann,Florenz Sasse,Heinrich Steinmetz,Irina Nickeleit,Nisar Malek,Ronald Frank

申请号：

BRPI0808035

公开号：

BRPI0808035A2

申请日:

2008.02.27

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27 for the treatment of cancer, as well as the derivatisation of said macrocycles. As an example argyrin A or argyrin F may be used.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/