Use of inhibitors of the degradation of p27, in particular Argyrin and derivatives thereof, for the treatment of proliferative diseases

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专利权人:

MEDIZINISCHE HOCHSCHULE HANNOVER;HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH

发明人:

MALEK, NISAR,NICKELEIT, IRINA,HINKELMANN, BETTINA,FRANK, RONALD,STEINMETZ, HEINRICH,SASSE, FLORENZ

申请号：

AU2008220967

公开号：

AU2008220967B2

申请日:

2008.02.27

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular Argyrin and derivatives thereof, preferably Argyrin A, for the treatment of proliferative diseases, such as cancer, as well as the derivatization of said macrocycles.

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中国工程科技知识中心

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