The Board of Trustees of the Leland Stanford Junior University
发明人:
Samuel Strober,Robert Lowsky
申请号：
US15914746
公开号：
US10076542B2
申请日:
2018.03.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to a recipient, where tolerance to the graft is established through development of a persistent mixed chimerism. An individual with persistent mixed chimerism, usually for a period of at least six months, is able to withdraw from the use of immunosuppressive drugs after a period of time sufficient to establish tolerance.
