THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
Samuel Strober,Robert Lowsky
申请号:
US14438159
公开号:
US20150272993A1
申请日:
2014.02.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to a recipient, where tolerance to the graft is established through development of a persistent mixed chimerism. An individual with persistent mixed chimerism, usually for a period of at least six months, is able to withdraw from the use of immunosuppressive drugs after a period of time sufficient to establish tolerance.