Embodiments of the invention are directed to methods and devices for providing instructions to treat and for treating patients through the use of medical devices. Some embodiments are particularly configured to treat musculoskeletal conditions by providing for alignment of bones by use of bone alignment devices in accordance with instructions provided through a prescription. Other embodiments may be capable of facilitating or providing revised prescriptions in response to treatment conditions. Embodiments may also provide effective ways of communicating prescription and compliance information between patients and health care providers.