histone deacetylase inhibitors for the treatment of Philadelphia negative myeloproliferative syndromes

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专利权人:

ITALFARMACO SPA

发明人:

BARBUI, TIZIANO,MASCAGNI, PAOLO,OLDONI, TIZIANO,RAMBALDI, ALESSANDRO

申请号：

BRPI0913699

公开号：

BRPI0913699A2

申请日:

2009.09.21

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The use of substances capable of inhibiting one or more enzymes of the histone deacetylase family (histone deacetylase inhibitors) for the therapeutic treatment of Philadelphia-negative myeloproliferative syndromes (polycythemia vera, essential thrombocythemia or idiopathic myelofibrosis) is described. The dosage of the above-mentioned substances is significantly lower than that normally used for the care of other tumor syndromes and may be from 10 to 150 mg/day/patient.

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