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ЗАКЛЮЧЕННЫЕ В ОБОЛОЧКУ НАНОКЛАСТЕРЫ ПЛАТИНЫ ДЛЯ ПРОТИВОРАКОВЫХ ХИМИОТЕРАПЕВТИЧЕСКИХ СРЕДСТВ
专利权人:
НЭШЕНЕЛ ХЕЛС РИСЁЧ ИНСТИТЬЮТС (TW)
发明人:
ЛИНЬ Шу-И (TW)
申请号:
RU2015135133
公开号:
RU2015135133A
申请日:
2014.02.18
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
A caged platinum nanocluster complex is disclosed. The complex comprises (a) an amine-terminated dendrimer and (b) a platinum nanocluster comprising platinum oxides, the platinum nanocluster being confined inside of the amine-terminated dendrimer. The complex exhibits cytotoxicity to cancer cells. A double-caged platinum nanocluster complex is also disclosed, which comprises polyethylene glycol (PEG) coated on the surface of a dendrimer caged platinum nanocluster complex. The double-caged caged platinum nanocluster complex comprises pH-sensitive bonds on the surface thereof. Also disclosed are methods of preparing and using the same.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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