LIPIDES CATIONIQUES POUR L'ADMINISTRATION D'ACIDES NUCLÉIQUES ET LEUR PRÉPARATION

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专利权人:

Ramot at Tel-Aviv University Ltd.

发明人:

PEER, Dan,RAMISHETTI, Srinivas

申请号：

EP17869620

公开号：

EP3538515A4

申请日:

2017.11.07

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention provides cationic lipids and lipid nanoparticle formulations comprising these lipids, alone or in combination with other lipids. These lipid nanoparticles may be formulated with nucleic acids to facilitate their intracellular delivery both in vitro and for therapeutic applications. The present invention also provides methods of chemical synthesis of these lipids, lipid nanoparticle preparation and formulation with nucleic acids.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/