ENDO, ATSUSHI,YU, ROBERT T.,FANG, FRANCIS,CHOI, HYEONG WOOK,SHAN, MINGDE
申请号:
CA2994842
公开号:
CA2994842A1
申请日:
2016.08.05
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
We provide diastereomerically pure or substantially diastereomerically pure activated phosphoramidochloridate morpholino nucleosides, methods of their preparation, and methods of their use in stereospecific coupling for stereospecific synthesis of diastereomerically pure phosphorodiamidate morpholino oligomers (PMOs).