BAGAL, SHARANJEET KAUR,KEMP, MARK IAN,MILLER, DUNCAN CHARLES,MURATA, YOSHIHISA
申请号:
SG11201401032Y
公开号:
SG11201401032YA
申请日:
2012.10.15
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
The present invention is directed to imidazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new imidazole NaV1.8 modulators of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. NaV1.8 modulators are useful in the treatment of a wide range of disorders, particularly pain.