Sharanjeet Kaur Bagal,Mark Ian Kemp,Duncan Charles Miller,Yoshihisa Murata
申请号:
US14351893
公开号:
US09079878B2
申请日:
2012.10.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is directed to imidazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new imidazole NaV1.8 modulators of formula (I):or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. NaV1.8 modulators are useful in the treatment of a wide range of disorders, particularly pain.