THE REGENTS OF THE UNIVERSITY OF MICHIGAN;UNIVERSITY OF NEWCASTLE UPON TYNE
发明人:
Alexander Rickard,Nick Jakubovics,Derek S. Samarian,Ethan Kolderman
申请号：
US15023111
公开号：
US20160235698A1
申请日:
2014.09.24
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present disclosure relates to compositions and methods for destabilizing biofilms, altering biofilm 3D structure, and dispersing biofilms, in order to enhance biofilm cell removal and/or sensitivity to other agents (e.g., environmental or co-applied treatments). In particular, the present disclosure relates to the use of L-arginine in the removal and/or sensitization (e.g., to antimicrobials) of microorganisms in medical, industrial, domestic, or environmental applications, as well as treatment of bacterial infections (e.g., in biofilms).
