THE REGENTS OF THE UNIVERSITY OF MICHIGAN;COLGATE-PALMOLIVE COMPANY
发明人:
Alexander Rickard,Adam Underwood,Laurence Du-Thumm
申请号:
US15134007
公开号:
US10570401B2
申请日:
2016.04.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure relates to compositions and methods for destabilizing biofilms, altering biofilm 3D structure, and dispersing biofilms, in order to enhance biofilm cell removal and/or sensitivity to other agents (e.g., environmental or co-applied treatments). In particular, the present disclosure relates to the use of L-arginine in the removal and/or sensitization (e.g., to antimicrobials) of microorganisms in medical, industrial, domestic, or environmental applications, as well as treatment of bacterial infections (e.g., in biofilms).