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COMPOSITIONS AND METHODS FOR MODULATING THROMBIN GENERATION
专利权人:
THE CHILDRENS HOSPITAL OF PHILADELPHIA
发明人:
CAMIRE, RODNEY M.,BUNCE, MATTHEW W.,BOS, METTINE H.A.
申请号:
CA2851844
公开号:
CA2851844A1
申请日:
2012.10.15
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
In accordance with the instant invention, Factor V peptides for the modulation of thrombin generation are provided. In a particular embodiment, the peptide has at least 80% homology with SEQ ID NO: 1, 2, 3 or 4. Nucleic acid molecules encoding the peptides are also encompassed by the instant invention. Compositions comprising at least one peptide and/or nucleic acid of the instant invention and at least one pharmaceutically acceptable earner are also provided. The compositions may further comprise at least one other anti-thrombosis compound.
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